ANTICOCCIDIAL SUSPENSION
FOR ORAL ADMINISTRATION

COMPOSITION :
Each 1 ml contains :
Toltrazuril ……………………………………… 25 mg

INDICATIONS:
For the treatment of coccidiosis caused by:
Chicken (pullets and breeders): Eimeria acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella.
Turkeys: Eimeria adenoides, E. meleagrimitis.
Calves: For the prevention of clinical signs of coccidiosis and reduction of coccidia shedding in housed calves replacing cows producing milk for human consumption (dairy cows) on farms with a confirmed history of coccidiosis caused by Eimeria bovis or Eimeria zuernii.
Lambs: For the prevention of clinical signs of coccidiosis and reduction of coccidia shedding in lambs on farms with a confirmed history of coccidiosis caused by Eimeria crandallis and Eimeria ovinoidalis.

DESCRIPTION:
Toltrazuril is an anticoccidial of the triazinetrione group, active against Eimeria spp. Its activity affects the intracellular development stages of the parasite without affecting the extracellular stages of the parasites.
At parasite level, toltrazuril decreases the enzymatic activity of the respiratory chain, causing inflammation of the endoplasmic reticulum and Golgi apparatus, perinuclear space modifications and alteration of division of the nucleus.
In chickens and turkeys, toltrazuril is absorbed at rate of at least 50%. Distribution is higher in liver and kidney. The active substance is rapidly metabolised and the main metabolite is characterised as a toltrazuril sulfone.

WITHDRAWAL PERIOD:
Poultry: Meat: 16 Days  Turkeys: Meat: 18 Days
Calves: Meat: 63 Days  Lambs: Meat: 42 Days
Eggs: Not used for layers producing eggs for human consumption.

DOSAGE AND ADMINISTRATION:

• Poultry & Turkeys:
  The recommended dose rate is 7 mg toltrazuril per kg of body weight (equivalent to 28 mL of medicinal product per 100 kg of body weight) daily given for 2 consecutive days.
• Calves:
  Each animal should be treated with a single oral dose of 15 mg toltrazuril/kg body weight corresponding to 6.0 mL oral suspension per 10 kg body weight.
• Lambs:
  Each animal should be treated with a single oral dose of 20 mg toltrazuril/kg body weight corresponding to 0.8 mL oral suspension per kg body weight.

Keep it in original container below 25°C.
USED FOR
Poultry, Calves, Lambs.

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