ANTIBIOTIC POWDER
For Oral Administration

COMPOSITION:
Each 1 gm contains:
Tylosin Tartrate 1000 mg

INDICATIONS:
For prevention and treatment of infections caused by tylosin-sensitive pathogenic microorganisms — mycoplasmosis, chronic respiratory disease, and infectious synovitis in chickens and turkeys; infectious sinusitis in turkeys; spirochetosis (borreliosis) in chickens; for prevention of liver abscesses (caused by Spherophorus necrophorus and Corynebacterium pyogenes) in calves for fattening.

SIDE EFFECTS:
Tylosin is well tolerated by treated animals and seldom induces undesirable effects.

WITHDRAWAL PERIOD:
For meat:

• Poultry: 0 day after the last administration.
• Calves: 14 days.
  For egg:
• Poultry: Do not use in layers producing eggs for human consumption.

DESCRIPTION:
Tylosin is a macrolide antibiotic with a bacteriostatic effect against Gram-positive and some Gram-negative microorganisms (Streptococcus spp., Staphylococcus spp., Erysipelothrix spp., Corynebacterium spp., Brachyspira, Serpulina (Treponema) hyodysenteriae, Borrelia, Spirochaeta spp., Campylobacter (Vibrio) coli, Pasteurella spp., Brucella spp., Rickettsia spp., Mycoplasma spp., and some large viruses), including also some anaerobic microorganisms (Fusobacterium spp., Bacteroides spp.).
It is active against Chlamydia spp. as well.
Tylosin does not act antimicrobially directly on bacteria of the family Enterobacteriaceae (E. coli, Salmonella spp.), but reveals an antibiotic activity by hindering their adhesion to the intestinal villi, penetrating the intestinal mucous membrane, and impeding colonization.
Tylosin proves also an anticoccidial activity, mostly against Eimeria tenella.

DOSAGE AND ADMINISTRATION:
It is recommended to mix the measured quantity of the preparation (calculated based on the prescribed dose) according to the following stages:

• Up to 10 kg feed
• Up to 100 kg feed
• Up to 1000 kg feed

Calves:
1020 mg tylosin per kg body weight (corresponding to 1122 mg of the veterinary medicinal product per kg BW), twice daily (corresponding to a daily dose of 2040 mg tylosin per kg BW) for 714 days.

Chickens:
For the treatment of chronic respiratory disease:
75100 mg tylosin per kg BW per day (corresponding to 82.5110 mg of the veterinary medicinal product per kg BW) for 35 days.
For the treatment of necrotic enteritis:
20 mg tylosin per kg BW per day (corresponding to 22 mg of the veterinary medicinal product) for 3 days.

Keep it in the original packing in a dry, dark place below 25°C

USED FOR
Calves and Chickens

Download PDF